3'-functionalized adamantyl cannabinoid receptor probes.

Ogawa, Go; Tius, Marcus A; Zhou, Han; Nikas, Spyros P; Halikhedkar, Aneetha; Mallipeddi, Srikrishnan; Makriyannis, Alexandros

Ogawa, Go; Tius, Marcus A; Zhou, Han; Nikas, Spyros P; Halikhedkar, Aneetha; Mallipeddi, Srikrishnan; Makriyannis, Alexandros.

Afiliação

Ogawa G; Department of Chemistry, University of Hawaii at Manoa, 2545 The Mall, Honolulu, Hawaii 96822, United States.
Tius MA; Department of Chemistry, University of Hawaii at Manoa, 2545 The Mall, Honolulu, Hawaii 96822, United States.
Zhou H; Center for Drug Discovery, Department of Chemistry and Chemical Biology, and Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Nikas SP; Center for Drug Discovery, Department of Chemistry and Chemical Biology, and Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Halikhedkar A; Center for Drug Discovery, Department of Chemistry and Chemical Biology, and Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Mallipeddi S; Center for Drug Discovery, Department of Chemistry and Chemical Biology, and Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Makriyannis A; Center for Drug Discovery, Department of Chemistry and Chemical Biology, and Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States.

J Med Chem ; 58(7): 3104-16, 2015 Apr 09.

Article em En | MEDLINE | ID: mdl-25760146

Assuntos

Adamantano/análogos & derivados; Sondas Moleculares/química; Receptores de Canabinoides/metabolismo; Adamantano/química; Animais; Canabinoides/química; Membrana Celular/metabolismo; Técnicas de Química Sintética; Células HEK293; Humanos; Conformação Molecular; Técnicas de Sonda Molecular; Sondas Moleculares/metabolismo; Ensaio Radioligante; Ratos; Receptor CB1 de Canabinoide/metabolismo; Receptor CB2 de Canabinoide/metabolismo; Relação Estrutura-Atividade

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adamantano / Sondas Moleculares / Receptores de Canabinoides Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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