Failure of intravitreal bevacizumab in the treatment of choroidal metastasis.
Eye (Lond)
; 29(5): 707-11, 2015 May.
Article
em En
| MEDLINE
| ID: mdl-25771814
ABSTRACT
BACKGROUND:
Metastasis to choroid is the most common intraocular malignancy, arising most frequently from carcinoma of breast in women and lung in men. Recent case reports have described successful use of intravitreal bevacizumab to achieve local control of such tumours. MATERIALS ANDMETHODS:
Five cases of choroidal metastases from varying primaries breast, lung, and colon were treated with intravitreal bevacizumab, and tumour response observed and documented with serial photographs and B-scans.RESULTS:
Four of the five tumours were seen to progress despite intravitreal bevacizumab treatment.CONCLUSIONS:
Intravitreal bevacizumab as the primary treatment of choroidal metastases is not recommended and should not delay more effective alternative treatments.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma
/
Adenocarcinoma
/
Neoplasias da Coroide
/
Inibidores da Angiogênese
/
Bevacizumab
/
Neoplasias Intestinais
Limite:
Adult
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eye (Lond)
Assunto da revista:
OFTALMOLOGIA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Reino Unido