Turning up the heat on membrane fluidity.

Fan, Weiwei; Evans, Ronald M

Fan, Weiwei; Evans, Ronald M.

Afiliação

Fan W; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Evans RM; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address: evans@salk.edu.

Cell ; 161(5): 962-963, 2015 May 21.

Article em En | MEDLINE | ID: mdl-26000475

ABSTRACT

ABSTRACT

How do cells maintain the fluidity of cellular membrane in response to temperature fluctuation? In this issue of Cell, Ma et al. identify a regulatory circuit involving a heat-induced acyl-CoA dehydrogenase that controls the lipid saturation level and the fluidity of cellular membranes by transcriptionally regulating a lipid desaturase.

Assuntos

Acil-CoA Desidrogenase/metabolismo; Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/fisiologia; Ácidos Graxos/metabolismo; Animais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / Acil-CoA Desidrogenase / Ácidos Graxos Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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