Secondary structure-based analysis of mouse brain small RNA sequences obtained by using next-generation sequencing.
Genomics
; 106(2): 122-8, 2015 Aug.
Article
em En
| MEDLINE
| ID: mdl-26003051
ABSTRACT
In order to find novel structured small RNAs, next-generation sequencing was applied to small RNA fractions with lengths ranging from 40 to 140 nt and secondary structure-based clustering was performed. Sequences of structured RNAs were effectively clustered and analyzed by secondary structure. Although more than 99% of the obtained sequences were known RNAs, 16 candidate mouse structured small non-coding RNAs (MsncRs) were isolated. Based on these results, the merits of secondary structure-based analysis are discussed.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Química Encefálica
/
Pequeno RNA não Traduzido
Limite:
Animals
Idioma:
En
Revista:
Genomics
Assunto da revista:
GENETICA
Ano de publicação:
2015
Tipo de documento:
Article