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Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma.
Posch, C; Cholewa, B D; Vujic, I; Sanlorenzo, M; Ma, J; Kim, S T; Kleffel, S; Schatton, T; Rappersberger, K; Gutteridge, R; Ahmad, N; Ortiz/Urda, S.
Afiliação
  • Posch C; University of California San Francisco, Department of Dermatology, Mt. Zion Cancer Research Center, 2340 Sutter Street N461, 94115 San Francisco - USA.
  • Cholewa BD; Brigham and Women's Hospital, Harvard Medical School, Department of Dermatology, 77 Avenue Louis Pasteur, 02115 Boston - USA.
  • Vujic I; The Rudolfstiftung Hospital, Academic Teaching Hospital, Medical University Vienna, Department of Dermatology, Juchgasse 25, 1030 Vienna - Austria.
  • Sanlorenzo M; University of Wisconsin, Department of Dermatology, 7418 Wisconsin Institutes for Medical Research, 1111 Highland Ave, Madison, WI 53705 - USA.
  • Ma J; University of California San Francisco, Department of Dermatology, Mt. Zion Cancer Research Center, 2340 Sutter Street N461, 94115 San Francisco - USA.
  • Kim ST; The Rudolfstiftung Hospital, Academic Teaching Hospital, Medical University Vienna, Department of Dermatology, Juchgasse 25, 1030 Vienna - Austria.
  • Kleffel S; University of California San Francisco, Department of Dermatology, Mt. Zion Cancer Research Center, 2340 Sutter Street N461, 94115 San Francisco - USA.
  • Schatton T; Department of Medical Sciences, Section of Dermatology, University of Turin - Italy.
  • Rappersberger K; University of California San Francisco, Department of Dermatology, Mt. Zion Cancer Research Center, 2340 Sutter Street N461, 94115 San Francisco - USA.
  • Gutteridge R; University of California San Francisco, Department of Dermatology, Mt. Zion Cancer Research Center, 2340 Sutter Street N461, 94115 San Francisco - USA.
  • Ahmad N; Brigham and Women's Hospital, Harvard Medical School, Department of Dermatology, 77 Avenue Louis Pasteur, 02115 Boston - USA.
  • Ortiz/Urda S; Brigham and Women's Hospital, Harvard Medical School, Department of Dermatology, 77 Avenue Louis Pasteur, 02115 Boston - USA.
J Invest Dermatol ; 135(10): 2475-2483, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26016894
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / MAP Quinase Quinase 1 / Inibidores de Proteínas Quinases / Melanoma Tipo de estudo: Clinical_trials Limite: Animals / Humans Idioma: En Revista: J Invest Dermatol Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / MAP Quinase Quinase 1 / Inibidores de Proteínas Quinases / Melanoma Tipo de estudo: Clinical_trials Limite: Animals / Humans Idioma: En Revista: J Invest Dermatol Ano de publicação: 2015 Tipo de documento: Article