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Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli.
Housley, William J; Fernandez, Salvador D; Vera, Kenneth; Murikinati, Sasidhar R; Grutzendler, Jaime; Cuerdon, Nicole; Glick, Laura; De Jager, Phillip L; Mitrovic, Mitja; Cotsapas, Chris; Hafler, David A.
Afiliação
  • Housley WJ; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA.
  • Fernandez SD; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA.
  • Vera K; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA.
  • Murikinati SR; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA.
  • Grutzendler J; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA.
  • Cuerdon N; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Glick L; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • De Jager PL; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Mitrovic M; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA.
  • Cotsapas C; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA. Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02142, USA. Department of Genetics, Yale School of Medicine, New Haven, CT 06511, USA.
  • Hafler DA; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06511, USA. Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA 02142, USA. david.hafler@yale.edu.
Sci Transl Med ; 7(291): 291ra93, 2015 Jun 10.
Article em En | MEDLINE | ID: mdl-26062845
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Autoimunidade / NF-kappa B / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Inflamação Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Autoimunidade / NF-kappa B / Predisposição Genética para Doença / Polimorfismo de Nucleotídeo Único / Inflamação Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos