Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-&#954;B activation mediated by IL-4/miR-324-5p/CUEDC2 axis.

Song, Lingqin; Liu, Di; Zhao, Yang; He, Jianjun; Kang, Huafeng; Dai, Zhijun; Wang, Xijing; Zhang, Shuqun; Zan, Ying

Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-κB activation mediated by IL-4/miR-324-5p/CUEDC2 axis.

Song, Lingqin; Liu, Di; Zhao, Yang; He, Jianjun; Kang, Huafeng; Dai, Zhijun; Wang, Xijing; Zhang, Shuqun; Zan, Ying.

Afiliação

Song L; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China. Electronic address: qinlingsongxa@163.com.
Liu D; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China.
Zhao Y; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China.
He J; Department of Surgical Oncology, The First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710061, China.
Kang H; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China.
Dai Z; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China.
Wang X; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China.
Zhang S; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China.
Zan Y; Department of Oncology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China.

Biochem Biophys Res Commun ; 464(3): 705-10, 2015 Aug 28.

Article em En | MEDLINE | ID: mdl-26166821

Assuntos

Neoplasias da Mama/tratamento farmacológico; Proteínas de Transporte/metabolismo; Interleucina-4/metabolismo; Proteínas de Membrana/metabolismo; MicroRNAs/metabolismo; Morfinanos/farmacologia; NF-kappa B/metabolismo; Proteínas Adaptadoras de Transdução de Sinal; Antineoplásicos Fitogênicos/administração & dosagem; Antineoplásicos Fitogênicos/farmacologia; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Relação Dose-Resposta a Droga; Feminino; Humanos; Proteínas I-kappa B/metabolismo; MicroRNAs/genética; Mimetismo Molecular; Morfinanos/administração & dosagem; NF-kappa B/antagonistas & inibidores; Invasividade Neoplásica/prevenção & controle; Fitoterapia

Palavras-chave

CUEDC2; IKK phosphorylation; Invasion and metastasis; NF-κB; Sinomenine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas de Transporte / NF-kappa B / Interleucina-4 / MicroRNAs / Proteínas de Membrana / Morfinanos Limite: Female / Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2015 Tipo de documento: Article

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