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A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo.
Yan, Clare S W; Wong, Iris L K; Chan, Kin-Fai; Kan, Jason W Y; Chong, Tsz Cheung; Law, Man Chun; Zhao, Yunzhe; Chan, Shun Wan; Chan, Tak Hang; Chow, Larry M C.
Afiliação
  • Yan CS; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Wong IL; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Chan KF; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Kan JW; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Chong TC; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Law MC; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Zhao Y; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Chan SW; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Chan TH; Department of Applied Biology and Chemical Technology and State Key Laboratory of Chirosciences, Hong Kong Polytechnic University , Hong Kong SAR, China.
  • Chow LM; Department of Chemistry, McGill University , Montreal, Quebec H3A 2K6, Canada.
Mol Pharm ; 12(10): 3507-17, 2015 Oct 05.
Article em En | MEDLINE | ID: mdl-26291333
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Flavonoides / Neoplasias da Mama / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Resistência a Múltiplos Medicamentos / Resistencia a Medicamentos Antineoplásicos / Flavonas / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Flavonoides / Neoplasias da Mama / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Resistência a Múltiplos Medicamentos / Resistencia a Medicamentos Antineoplásicos / Flavonas / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China