Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling.

Kaduwal, Saluja; Jeong, Woo-Jeong; Park, Jong-Chan; Lee, Kug Hwa; Lee, Young-Mi; Jeon, Soung-Hoo; Lim, Yong-Beom; Min, Do Sik; Choi, Kang-Yell

Kaduwal, Saluja; Jeong, Woo-Jeong; Park, Jong-Chan; Lee, Kug Hwa; Lee, Young-Mi; Jeon, Soung-Hoo; Lim, Yong-Beom; Min, Do Sik; Choi, Kang-Yell.

Afiliação

Kaduwal S; Translational Research Center for Protein Function Control, Yonsei University, Seoul, 120-749, Korea.
Jeong WJ; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, Korea.
Park JC; Translational Research Center for Protein Function Control, Yonsei University, Seoul, 120-749, Korea.
Lee KH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, Korea.
Lee YM; Translational Research Center for Protein Function Control, Yonsei University, Seoul, 120-749, Korea.
Jeon SH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, Korea.
Lim YB; Translational Research Center for Protein Function Control, Yonsei University, Seoul, 120-749, Korea.
Min do S; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, Korea.
Choi KY; Translational Research Center for Protein Function Control, Yonsei University, Seoul, 120-749, Korea.

Oncotarget ; 6(32): 33091-105, 2015 Oct 20.

Article em En | MEDLINE | ID: mdl-26384305

Assuntos

Movimento Celular/fisiologia; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas ras/metabolismo; Animais; Linhagem Celular Tumoral; Fator de Crescimento Epidérmico/metabolismo; Células HEK293; Humanos; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/secundário; Melanoma Experimental/metabolismo; Melanoma Experimental/patologia; Camundongos; Células NIH 3T3; Metástase Neoplásica; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais; Quinases raf/metabolismo; Proteínas ras/genética

Palavras-chave

PI3K; Ras; Sur8; cell migration; metastasis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Movimento Celular / Proteínas ras / Fosfatidilinositol 3-Quinases / Peptídeos e Proteínas de Sinalização Intracelular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article

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