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The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.
Blanco, F F; Jimbo, M; Wulfkuhle, J; Gallagher, I; Deng, J; Enyenihi, L; Meisner-Kober, N; Londin, E; Rigoutsos, I; Sawicki, J A; Risbud, M V; Witkiewicz, A K; McCue, P A; Jiang, W; Rui, H; Yeo, C J; Petricoin, E; Winter, J M; Brody, J R.
Afiliação
  • Blanco FF; Department of Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Jimbo M; Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • Wulfkuhle J; Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • Gallagher I; Center for Applied Proteomics and Molecular Medicine, School of Systems Biology, George Mason University, Manassas, VA, USA.
  • Deng J; Center for Applied Proteomics and Molecular Medicine, School of Systems Biology, George Mason University, Manassas, VA, USA.
  • Enyenihi L; Center for Applied Proteomics and Molecular Medicine, School of Systems Biology, George Mason University, Manassas, VA, USA.
  • Meisner-Kober N; Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • Londin E; Novartis Institutes for Biomedical Research, Novartis, Switzerland.
  • Rigoutsos I; Center for Computational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
  • Sawicki JA; Center for Computational Medicine, Thomas Jefferson University, Philadelphia, PA, USA.
  • Risbud MV; Lankenau Institute for Medical Research, Philadelphia, PA, USA.
  • Witkiewicz AK; Department of Orthopedic Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • McCue PA; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Jiang W; Department of Pathology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Rui H; Department of Pathology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Yeo CJ; Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Petricoin E; Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • Winter JM; Center for Applied Proteomics and Molecular Medicine, School of Systems Biology, George Mason University, Manassas, VA, USA.
  • Brody JR; Department of Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Oncogene ; 35(19): 2529-41, 2016 05.
Article em En | MEDLINE | ID: mdl-26387536
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Regulação Neoplásica da Expressão Gênica / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-pim-1 / Proteína Semelhante a ELAV 1 Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Regulação Neoplásica da Expressão Gênica / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-pim-1 / Proteína Semelhante a ELAV 1 Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos