The Effect of Omega-3 Docosahexaenoic Acid Supplementation on Gestational Length: Randomized Trial of Supplementation Compared to Nutrition Education for Increasing n-3 Intake from Foods.
Biomed Res Int
; 2015: 123078, 2015.
Article
em En
| MEDLINE
| ID: mdl-26413500
ABSTRACT
OBJECTIVE:
DHA supplementation was compared to nutrition education to increase DHA consumption from fish and DHA fortified foods.DESIGN:
This two-part intervention included a randomized double-blind placebo controlled DHA supplementation arm and a nutrition education arm designed to increase intake of DHA from dietary sources by 300 mg per day.SETTING:
Denver Health Hospitals and Clinics, Denver, Colorado, USA. POPULATION 871 pregnant women aged 18-40 were recruited between 16 and 20 weeks of gestation of whom 564 completed the study and complete delivery data was available in 505 women and infants.METHODS:
Subjects received either 300 or 600 mg DHA or olive oil placebo or nutrition education. MAIN OUTCOME VARIABLE Gestational length.RESULTS:
Gestational length was significantly increased by 4.0-4.5 days in women supplemented with 600 mg DHA per day or provided with nutrition education. Each 1% increase in RBC DHA at delivery was associated with a 1.6-day increase in gestational length. No significant effects on birth weight, birth length, or head circumference were demonstrated. The rate of early preterm birth (1.7%) in those supplemented with DHA (combined 300 and 600 mg/day) was significantly lower than in controls.CONCLUSION:
Nutrition education or supplementation with DHA can be effective in increasing gestational length.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cuidado Pré-Natal
/
Estatura
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Ácidos Docosa-Hexaenoicos
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Educação em Saúde
/
Suplementos Nutricionais
/
Dieta
Tipo de estudo:
Clinical_trials
Limite:
Adult
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Female
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Humans
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Newborn
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Pregnancy
Idioma:
En
Revista:
Biomed Res Int
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Estados Unidos