Your browser doesn't support javascript.
loading
Ferrocyanide-Ferricyanide Redox Couple Induced Electrochemiluminescence Amplification of Carbon Dots for Ultrasensitive Sensing of Glutathione.
Niu, Wen-Jun; Zhu, Rong-Hui; Cosnier, Serge; Zhang, Xue-Ji; Shan, Dan.
Afiliação
  • Niu WJ; Sino-French Laboratory of Biomaterials and Bioanalytical Chemistry, School of Environmental and Biological Engineering, Nanjing University of Science and Technology , Nanjing, Jiangsu Province 210094, China.
  • Zhu RH; Sino-French Laboratory of Biomaterials and Bioanalytical Chemistry, School of Environmental and Biological Engineering, Nanjing University of Science and Technology , Nanjing, Jiangsu Province 210094, China.
  • Cosnier S; University of Grenoble Alpes-CNRS, DCM UMR 5250, F-38000 Grenoble, France.
  • Zhang XJ; Sino-French Laboratory of Biomaterials and Bioanalytical Chemistry, School of Environmental and Biological Engineering, Nanjing University of Science and Technology , Nanjing, Jiangsu Province 210094, China.
  • Shan D; Sino-French Laboratory of Biomaterials and Bioanalytical Chemistry, School of Environmental and Biological Engineering, Nanjing University of Science and Technology , Nanjing, Jiangsu Province 210094, China.
Anal Chem ; 87(21): 11150-6, 2015 Nov 03.
Article em En | MEDLINE | ID: mdl-26478177
Here we report a novel solid-state ECL sensor for ultrasensitive sensing of glutathione (GSH) based on ferrocyanide-ferricyanide redox couple (Fe(CN)6(3-/4-)) induced electrochemiluminescence (ECL) amplification of carbon dots (C-dots). The electropolymerization of C-dots and (11-pyrrolyl-1-yl-undecyl) triethylammonium tetrafluoroborate (A2) enabled immobilization of the hydrophilic C-dots on the surface of glassy carbon electrode (GCE) perfectly, while the excellent conductivity of polypyrrole was exploited to accelerate electron transfer between them. The Fe(CN)6(3-/4-) can expeditiously convert the C-dots and S2O8(2-) to C-dot(•-) and SO4(•-), respectively. High yields of the excited state C-dots (C-dots*) were obtained, and a ∼10-fold ECL amplification was realized. The C-dots* obtained through the recombination of electron-injected and hole-injected processes may be impeded due to the interference of GSH to K2S2O8. Therefore, the constructed sensor for GSH showed a detection limit down to 54.3 nM (S/N = 3) and a wide linear range from 0.1-1.0 µM with a correlation coefficient of 0.997.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carbono / Técnicas Eletroquímicas / Ferricianetos / Ferrocianetos / Glutationa Idioma: En Revista: Anal Chem Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carbono / Técnicas Eletroquímicas / Ferricianetos / Ferrocianetos / Glutationa Idioma: En Revista: Anal Chem Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China