Next-Generation Sequencing and In Silico Analysis Facilitate Prolonged Response to Pazopanib in a Patient With Metastatic Urothelial Carcinoma of the Renal Pelvis.

Hahn, Andrew W; Giri, Smith; Patel, Dilan; Sluder, Heather; Vanderwalde, Ari; Martin, Mike G

Hahn, Andrew W; Giri, Smith; Patel, Dilan; Sluder, Heather; Vanderwalde, Ari; Martin, Mike G.

Afiliação

Hahn AW; From the Department of Internal Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee; Department of Internal Medicine, Washington University in St. Louis, St. Louis, Missouri; and Department of Hematology/Oncology, The West Cancer Center, Memphis, Tennessee.
Giri S; From the Department of Internal Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee; Department of Internal Medicine, Washington University in St. Louis, St. Louis, Missouri; and Department of Hematology/Oncology, The West Cancer Center, Memphis, Tennessee.
Patel D; From the Department of Internal Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee; Department of Internal Medicine, Washington University in St. Louis, St. Louis, Missouri; and Department of Hematology/Oncology, The West Cancer Center, Memphis, Tennessee.
Sluder H; From the Department of Internal Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee; Department of Internal Medicine, Washington University in St. Louis, St. Louis, Missouri; and Department of Hematology/Oncology, The West Cancer Center, Memphis, Tennessee.
Vanderwalde A; From the Department of Internal Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee; Department of Internal Medicine, Washington University in St. Louis, St. Louis, Missouri; and Department of Hematology/Oncology, The West Cancer Center, Memphis, Tennessee. From the Depar
Martin MG; From the Department of Internal Medicine, The University of Tennessee Health Science Center, Memphis, Tennessee; Department of Internal Medicine, Washington University in St. Louis, St. Louis, Missouri; and Department of Hematology/Oncology, The West Cancer Center, Memphis, Tennessee. From the Depar

J Natl Compr Canc Netw ; 13(10): 1181-5, 2015 Oct.

Article em En | MEDLINE | ID: mdl-26483058

Assuntos

Carcinoma de Células de Transição/genética; Proteínas Proto-Oncogênicas c-kit/genética; Receptor ErbB-2/genética; Receptor beta de Fator de Crescimento Derivado de Plaquetas/genética; Carcinoma de Células de Transição/tratamento farmacológico; Carcinoma de Células de Transição/patologia; Simulação por Computador; Feminino; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Indazóis; Pelve Renal/efeitos dos fármacos; Pelve Renal/patologia; Pessoa de Meia-Idade; Modelos Moleculares; Mutação; Metástase Neoplásica; Proteínas Proto-Oncogênicas c-kit/química; Pirimidinas/uso terapêutico; Receptor ErbB-2/química; Receptor beta de Fator de Crescimento Derivado de Plaquetas/química; Sulfonamidas/uso terapêutico; Urotélio/efeitos dos fármacos; Urotélio/patologia

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células de Transição / Receptor ErbB-2 / Proteínas Proto-Oncogênicas c-kit / Receptor beta de Fator de Crescimento Derivado de Plaquetas Tipo de estudo: Guideline / Prognostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: J Natl Compr Canc Netw Assunto da revista: NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article

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