FGF2-mediated reciprocal tumor cell-endothelial cell interplay contributes to the growth of chemoresistant cells: a potential mechanism for superficial bladder cancer recurrence.

Chen, Yule; Zhu, Guodong; Wu, Kaijie; Gao, Yang; Zeng, Jin; Shi, Qi; Guo, Peng; Wang, Xinyang; Chang, Luke S; Li, Lei; He, Dalin

Chen, Yule; Zhu, Guodong; Wu, Kaijie; Gao, Yang; Zeng, Jin; Shi, Qi; Guo, Peng; Wang, Xinyang; Chang, Luke S; Li, Lei; He, Dalin.

Afiliação

Chen Y; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Zhu G; Oncology Research Laboratory, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an, People's Republic of China.
Wu K; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Gao Y; Oncology Research Laboratory, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an, People's Republic of China.
Zeng J; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Shi Q; Oncology Research Laboratory, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an, People's Republic of China.
Guo P; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Wang X; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
Chang LS; Oncology Research Laboratory, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an, People's Republic of China.
Li L; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
He D; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.

Tumour Biol ; 37(4): 4313-21, 2016 Apr.

Article em En | MEDLINE | ID: mdl-26493998

Assuntos

Proliferação de Células/genética; Fator 2 de Crescimento de Fibroblastos/genética; Recidiva Local de Neoplasia/tratamento farmacológico; Neoplasias da Bexiga Urinária/tratamento farmacológico; Animais; Proliferação de Células/efeitos dos fármacos; Quimioterapia Adjuvante; Técnicas de Cocultura; Meios de Cultivo Condicionados; Doxorrubicina/administração & dosagem; Resistencia a Medicamentos Antineoplásicos/genética; Células Endoteliais/efeitos dos fármacos; Células Endoteliais/metabolismo; Feminino; Fator 2 de Crescimento de Fibroblastos/biossíntese; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Humanos; Masculino; Camundongos; Recidiva Local de Neoplasia/genética; Recidiva Local de Neoplasia/patologia; Neoplasias da Bexiga Urinária/genética; Neoplasias da Bexiga Urinária/patologia; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

Bladder cancer; Chemoresistance; Endothelial cell; FGF2; Recurrence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Bexiga Urinária / Fator 2 de Crescimento de Fibroblastos / Proliferação de Células / Recidiva Local de Neoplasia Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Tumour Biol Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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