&#945;-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol.

Abu-Fanne, Rami; Maraga, Emad; Abd-Elrahman, Ihab; Hankin, Aviel; Blum, Galia; Abdeen, Suhair; Hijazi, Nuha; Cines, Douglas B; Higazi, Abd Al-Roof

α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol.

Abu-Fanne, Rami; Maraga, Emad; Abd-Elrahman, Ihab; Hankin, Aviel; Blum, Galia; Abdeen, Suhair; Hijazi, Nuha; Cines, Douglas B; Higazi, Abd Al-Roof.

Afiliação

Abu-Fanne R; From the Department of Clinical Biochemistry and.
Maraga E; From the Department of Clinical Biochemistry and.
Abd-Elrahman I; the School of Pharmacy, Hadassah-Hebrew University, Jerusalem IL-91120, Israel and.
Hankin A; From the Department of Clinical Biochemistry and.
Blum G; the School of Pharmacy, Hadassah-Hebrew University, Jerusalem IL-91120, Israel and.
Abdeen S; From the Department of Clinical Biochemistry and.
Hijazi N; From the Department of Clinical Biochemistry and.
Cines DB; the Department of Pathology and Laboratory Medicine, Perelman School of Medicine-University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Higazi AA; From the Department of Clinical Biochemistry and the Department of Pathology and Laboratory Medicine, Perelman School of Medicine-University of Pennsylvania, Philadelphia, Pennsylvania 19104 higazi@mail.med.upenn.edu.

J Biol Chem ; 291(6): 2777-86, 2016 Feb 05.

Article em En | MEDLINE | ID: mdl-26518877

Assuntos

Aterosclerose/sangue; Colesterol/sangue; Células Endoteliais/metabolismo; Lipoproteínas LDL/sangue; Processamento de Proteína Pós-Traducional; alfa-Defensinas/sangue; Animais; Aterosclerose/genética; Aterosclerose/patologia; Catepsinas/sangue; Catepsinas/genética; Colesterol/genética; Colchicina/farmacologia; Células Endoteliais/patologia; Humanos; Inflamação/sangue; Inflamação/genética; Inflamação/patologia; Lipoproteínas LDL/genética; Masculino; Camundongos; Camundongos Transgênicos; Complexos Multiproteicos/sangue; Complexos Multiproteicos/genética; alfa-Defensinas/genética

Palavras-chave

atherosclerosis; defensin; lipoprotein; low density lipoprotein (LDL); neutrophil; α-defensins

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Processamento de Proteína Pós-Traducional / Colesterol / Alfa-Defensinas / Células Endoteliais / Aterosclerose / Lipoproteínas LDL Limite: Animals / Humans / Male Idioma: En Revista: J Biol Chem Ano de publicação: 2016 Tipo de documento: Article

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