A Herpes Simplex Virus 2 (HSV-2) gD Mutant Impaired for Neural Tropism Is Superior to an HSV-2 gD Subunit Vaccine To Protect Animals from Challenge with HSV-2.

Wang, Kening; Goodman, Kyle N; Li, Daniel Y; Raffeld, Mark; Chavez, Mayra; Cohen, Jeffrey I

Wang, Kening; Goodman, Kyle N; Li, Daniel Y; Raffeld, Mark; Chavez, Mayra; Cohen, Jeffrey I.

Afiliação

Wang K; Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA kwang@niaid.nih.gov jcohen@niaid.nih.gov.
Goodman KN; Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Li DY; Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Raffeld M; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Chavez M; Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Cohen JI; Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA kwang@niaid.nih.gov jcohen@niaid.nih.gov.

J Virol ; 90(1): 562-74, 2016 01 01.

Article em En | MEDLINE | ID: mdl-26559846

Assuntos

Herpesvirus Humano 2/imunologia; Herpesvirus Humano 2/fisiologia; Vacinas contra Herpesvirus/imunologia; Proteínas do Envelope Viral/imunologia; Tropismo Viral; Animais; Linhagem Celular; Feminino; Instabilidade Genômica; Herpesvirus Humano 2/genética; Vacinas contra Herpesvirus/administração & dosagem; Vacinas contra Herpesvirus/genética; Injeções Intramusculares; Camundongos Endogâmicos BALB C; Inoculações Seriadas; Vacinas Atenuadas/administração & dosagem; Vacinas Atenuadas/genética; Vacinas Atenuadas/imunologia; Vacinas de Subunidades Antigênicas/administração & dosagem; Vacinas de Subunidades Antigênicas/genética; Vacinas de Subunidades Antigênicas/imunologia; Vagina/virologia; Proteínas do Envelope Viral/genética; Carga Viral

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Envelope Viral / Herpesvirus Humano 2 / Vacinas contra Herpesvirus / Tropismo Viral Limite: Animals Idioma: En Revista: J Virol Ano de publicação: 2016 Tipo de documento: Article

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