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Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG-positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression.
Böttcher, R; Henderson, D J P; Dulla, K; van Strijp, D; Waanders, L F; Tevz, G; Lehman, M L; Merkle, D; van Leenders, G J L H; Baillie, G S; Jenster, G; Houslay, M D; Hoffmann, R.
Afiliação
  • Böttcher R; Department of Urology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands.
  • Henderson DJ; Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow G12 8TA, Scotland.
  • Dulla K; Departments of Oncology Solutions and Precision Diagnostics, Philips Research Europe, Eindhoven 5656 AE, The Netherlands.
  • van Strijp D; Departments of Oncology Solutions and Precision Diagnostics, Philips Research Europe, Eindhoven 5656 AE, The Netherlands.
  • Waanders LF; Departments of Oncology Solutions and Precision Diagnostics, Philips Research Europe, Eindhoven 5656 AE, The Netherlands.
  • Tevz G; Departments of Oncology Solutions and Precision Diagnostics, Philips Research Europe, Eindhoven 5656 AE, The Netherlands.
  • Lehman ML; Australian Prostate Cancer Research Centre-Institute of Health and Biomedical Innovation, University of Technology, and Translational Research Institute, Brisbane, Queensland 4102, Australia.
  • Merkle D; Australian Prostate Cancer Research Centre-Institute of Health and Biomedical Innovation, University of Technology, and Translational Research Institute, Brisbane, Queensland 4102, Australia.
  • van Leenders GJ; Departments of Oncology Solutions and Precision Diagnostics, Philips Research Europe, Eindhoven 5656 AE, The Netherlands.
  • Baillie GS; Department of Pathology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands.
  • Jenster G; Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow G12 8TA, Scotland.
  • Houslay MD; Department of Urology, Erasmus Medical Center, Rotterdam 3000 CA, The Netherlands.
  • Hoffmann R; Institute of Pharmaceutical Science, King's College London, London WC2R 2LS, UK.
Br J Cancer ; 113(10): 1502-11, 2015 Nov 17.
Article em En | MEDLINE | ID: mdl-26575822

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Proteínas de Fusão Oncogênica / Nucleotídeo Cíclico Fosfodiesterase do Tipo 4 Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Br J Cancer Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Proteínas de Fusão Oncogênica / Nucleotídeo Cíclico Fosfodiesterase do Tipo 4 Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Br J Cancer Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda