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CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common ß chain of the IL-3, GM-CSF and IL-5 receptors.
Panousis, Con; Dhagat, Urmi; Edwards, Kirsten M; Rayzman, Veronika; Hardy, Matthew P; Braley, Hal; Gauvreau, Gail M; Hercus, Timothy R; Smith, Steven; Sehmi, Roma; McMillan, Laura; Dottore, Mara; McClure, Barbara J; Fabri, Louis J; Vairo, Gino; Lopez, Angel F; Parker, Michael W; Nash, Andrew D; Wilson, Nicholas J; Wilson, Michael J; Owczarek, Catherine M.
Afiliação
  • Panousis C; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Dhagat U; b Australian Cancer Research Foundation Rational Drug Discovery Center, St. Vincent's Institute of Medical Research , Fitzroy , Victoria , 3065 , Australia.
  • Edwards KM; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Rayzman V; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Hardy MP; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Braley H; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Gauvreau GM; c McMaster University , Hamilton , Ontario L8N 3Z5 , Canada.
  • Hercus TR; d Division of Human Immunology, the Center for Cancer Biology, SA Pathology and the University of South Australia, Frome Road, Adelaide, South Australia 5000 and the University of South Australia , Adelaide , South Australia 5001 , Australia.
  • Smith S; c McMaster University , Hamilton , Ontario L8N 3Z5 , Canada.
  • Sehmi R; c McMaster University , Hamilton , Ontario L8N 3Z5 , Canada.
  • McMillan L; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Dottore M; d Division of Human Immunology, the Center for Cancer Biology, SA Pathology and the University of South Australia, Frome Road, Adelaide, South Australia 5000 and the University of South Australia , Adelaide , South Australia 5001 , Australia.
  • McClure BJ; d Division of Human Immunology, the Center for Cancer Biology, SA Pathology and the University of South Australia, Frome Road, Adelaide, South Australia 5000 and the University of South Australia , Adelaide , South Australia 5001 , Australia.
  • Fabri LJ; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Vairo G; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Lopez AF; d Division of Human Immunology, the Center for Cancer Biology, SA Pathology and the University of South Australia, Frome Road, Adelaide, South Australia 5000 and the University of South Australia , Adelaide , South Australia 5001 , Australia.
  • Parker MW; b Australian Cancer Research Foundation Rational Drug Discovery Center, St. Vincent's Institute of Medical Research , Fitzroy , Victoria , 3065 , Australia.
  • Nash AD; e Department of Biochemistry and Molecular Biology , Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville , Victoria 3010 , Australia.
  • Wilson NJ; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Wilson MJ; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
  • Owczarek CM; a Research and Development, CSL Limited; Bio21 Molecular Science and Biotechnology Institute , Parkville Victoria , 3010 , Australia.
MAbs ; 8(3): 436-53, 2016.
Article em En | MEDLINE | ID: mdl-26651396
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator Estimulador de Colônias de Granulócitos e Macrófagos / Interleucina-5 / Interleucina-3 / Subunidade beta Comum dos Receptores de Citocinas / Anticorpos Monoclonais Murinos / Epitopos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator Estimulador de Colônias de Granulócitos e Macrófagos / Interleucina-5 / Interleucina-3 / Subunidade beta Comum dos Receptores de Citocinas / Anticorpos Monoclonais Murinos / Epitopos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Austrália