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Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations.
Duru, Valentine; Khim, Nimol; Leang, Rithea; Kim, Saorin; Domergue, Anais; Kloeung, Nimol; Ke, Sopheakvatey; Chy, Sophy; Eam, Rotha; Khean, Chanra; Loch, Kaknika; Ken, Malen; Lek, Dysoley; Beghain, Johann; Ariey, Frédéric; Guerin, Philippe J; Huy, Rekol; Mercereau-Puijalon, Odile; Witkowski, Benoit; Menard, Didier.
Afiliação
  • Duru V; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. vduru@pasteur-kh.org.
  • Khim N; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. knimol@pasteur-kh.org.
  • Leang R; National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia. rithealeang@gmail.com.
  • Kim S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. ksaorin@pasteur-kh.org.
  • Domergue A; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. adomergue@pasteur-kh.org.
  • Kloeung N; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. klnimol@pasteur-kh.org.
  • Ke S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. ksopheakvatey@pasteur-kh.org.
  • Chy S; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. chsophy@pasteur-kh.org.
  • Eam R; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. rotha@pasteur-kh.org.
  • Khean C; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. kchanra@pasteur-kh.org.
  • Loch K; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. lkaknika@pasteur-kh.org.
  • Ken M; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. kmalen@pasteur-kh.org.
  • Lek D; National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia. soleycnm@gmail.com.
  • Beghain J; Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France. johann.beghain@wanadoo.fr.
  • Ariey F; Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France. frederic.ariey@pasteur.fr.
  • Guerin PJ; WorldWide Antimalarial Resistance Network, Oxford, UK. philippe.guerin@wwarn.org.
  • Huy R; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Oxford University, Oxford, UK. philippe.guerin@wwarn.org.
  • Mercereau-Puijalon O; National Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia. kolhuy@gmail.com.
  • Witkowski B; Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France. omp@pasteur.fr.
  • Menard D; Malaria Molecular Epidemiology Unit, Institut Pasteur du Cambodge, 5 Boulevard Monivong, BP 983, Phnom Penh, Cambodia. bwitkowski@pasteur-kh.org.
BMC Med ; 13: 305, 2015 Dec 22.
Article em En | MEDLINE | ID: mdl-26695060
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Quinolinas / Artemisininas Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Animals / Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: BMC Med Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Camboja
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Quinolinas / Artemisininas Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Animals / Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: BMC Med Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Camboja