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Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse.
Coelho, Paula A; Bury, Leah; Shahbazi, Marta N; Liakath-Ali, Kifayathullah; Tate, Peri H; Wormald, Sam; Hindley, Christopher J; Huch, Meritxell; Archer, Joy; Skarnes, William C; Zernicka-Goetz, Magdalena; Glover, David M.
Afiliação
  • Coelho PA; Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK.
  • Bury L; Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK.
  • Shahbazi MN; Department of Physiology, Development and Neuroscience, Physiological Laboratory, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.
  • Liakath-Ali K; Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK Centre for Stem Cells and Regenerative Medicine, King's College London, Floor 28, Tower Wing, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.
  • Tate PH; Wellcome Trust Genome Campus, the Wellcome Trust Sanger Institute, Cambridge, Hinxton CB10 1SA, UK.
  • Wormald S; Wellcome Trust Genome Campus, the Wellcome Trust Sanger Institute, Cambridge, Hinxton CB10 1SA, UK.
  • Hindley CJ; Henry Wellcome Building of Cancer and Developmental Biology, the Wellcome Trust/Cancer Research UK Gurdon Institute, Tennis Court Road, Cambridge CB2 1QN, UK.
  • Huch M; Henry Wellcome Building of Cancer and Developmental Biology, the Wellcome Trust/Cancer Research UK Gurdon Institute, Tennis Court Road, Cambridge CB2 1QN, UK.
  • Archer J; Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.
  • Skarnes WC; Wellcome Trust Genome Campus, the Wellcome Trust Sanger Institute, Cambridge, Hinxton CB10 1SA, UK.
  • Zernicka-Goetz M; Department of Physiology, Development and Neuroscience, Physiological Laboratory, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.
  • Glover DM; Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK dmg25@hermes.cam.ac.uk.
Open Biol ; 5(12): 150209, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26701933

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cílios / Proteínas Serina-Treonina Quinases / Centrossomo / Hiperplasia Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Open Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cílios / Proteínas Serina-Treonina Quinases / Centrossomo / Hiperplasia Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Open Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido