Layer-by-Layer Assembly of Metal-Organic Frameworks in Macroporous Polymer Monolith and Their Use for Enzyme Immobilization.
Macromol Rapid Commun
; 37(6): 551-7, 2016 Mar.
Article
em En
| MEDLINE
| ID: mdl-26806691
ABSTRACT
New monolithic materials comprising zeolitic imidazolate framework (ZIF-8) located on the pore surface of poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolith previously functionalized with N-(3-aminopropyl)-imidazole have been prepared via a layer-by-layer self-assembly strategy. These new ZIF-8@monolith hybrids are used as solid-phase carriers for enzyme immobilization. Their performance is demonstrated with immobilization of a model proteolytic enzyme trypsin. The best of the conjugates enable very efficient digestion of proteins that can be achieved in mere 43 s.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tripsina
/
Propanóis
/
Enzimas Imobilizadas
/
Imidazóis
/
Metilmetacrilatos
Limite:
Animals
Idioma:
En
Revista:
Macromol Rapid Commun
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
China