Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol.

Tao, Wensi; Moore, Robert; Meng, Yue; Smith, Elizabeth R; Xu, Xiang-Xi

Tao, Wensi; Moore, Robert; Meng, Yue; Smith, Elizabeth R; Xu, Xiang-Xi.

Afiliação

Tao W; Department of Cell Biology, Molecular Cell and Developmental Biology Graduate Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136.
Moore R; Department of Cell Biology, Molecular Cell and Developmental Biology Graduate Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136.
Meng Y; Department of Cell Biology, Molecular Cell and Developmental Biology Graduate Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136.
Smith ER; Department of Cell Biology, Molecular Cell and Developmental Biology Graduate Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136.
Xu XX; Department of Cell Biology, Molecular Cell and Developmental Biology Graduate Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136 xxu2@med.miami.edu.

J Lipid Res ; 57(5): 809-17, 2016 05.

Article em En | MEDLINE | ID: mdl-27005486

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/fisiologia; Proteínas Adaptadoras de Transporte Vesicular/fisiologia; Colesterol/sangue; Endocitose; Hipercolesterolemia/sangue; Animais; Proteínas Reguladoras de Apoptose; Aterosclerose/sangue; Aterosclerose/etiologia; Células Cultivadas; Feminino; Expressão Gênica; Homeostase; Hipercolesterolemia/complicações; Lipoproteínas LDL/metabolismo; Masculino; Camundongos da Linhagem 129; Camundongos Endogâmicos C57BL; Camundongos Knockout; Receptores de LDL/genética; Receptores de LDL/metabolismo

Palavras-chave

Disabled-2; autosomal recessive hypercholesterolemia; endocytic trafficking; low density liproprotein; low density liproprotein receptor; serum cholesterol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colesterol / Proteínas Adaptadoras de Transporte Vesicular / Proteínas Adaptadoras de Transdução de Sinal / Endocitose / Hipercolesterolemia Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: J Lipid Res Ano de publicação: 2016 Tipo de documento: Article

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