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Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling.
Morello, Giovanna; Imperatore, Roberta; Palomba, Letizia; Finelli, Carmine; Labruna, Giuseppe; Pasanisi, Fabrizio; Sacchetti, Lucia; Buono, Lorena; Piscitelli, Fabiana; Orlando, Pierangelo; Di Marzo, Vincenzo; Cristino, Luigia.
Afiliação
  • Morello G; Institute of Biomolecular Chemistry, National Research Council, 80078 Pozzuoli, Italy; Department of Neurological and Movement Sciences, University of Verona, 37137 Verona, Italy;
  • Imperatore R; Institute of Biomolecular Chemistry, National Research Council, 80078 Pozzuoli, Italy;
  • Palomba L; Department of Biomolecular Sciences, University of Urbino "Carlo Bo," 61029 Urbino, Italy;
  • Finelli C; Interuniversity Center for Research and Study of Obesity, Department of Clinical and Experimental Medicine, Federico II University Hospital, 80131 Naples, Italy;
  • Labruna G; Istituto di Ricovero e Cura a Carattere Scientifico, Institute of Diagnostic and Nuclear Research, 80131 Naples, Italy;
  • Pasanisi F; Interuniversity Center for Research and Study of Obesity, Department of Clinical and Experimental Medicine, Federico II University Hospital, 80131 Naples, Italy;
  • Sacchetti L; Centro di Ingegneria Genetica-Advanced Biotechnology (Società Cooperativa a Responsabilità Limitata), 80131 Naples, Italy;
  • Buono L; Institute of Biomolecular Chemistry, National Research Council, 80078 Pozzuoli, Italy; Centro de Biología Molecular "Severo Ochoa," Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, 28049 Cantoblanco, Spain;
  • Piscitelli F; Institute of Biomolecular Chemistry, National Research Council, 80078 Pozzuoli, Italy;
  • Orlando P; Institute of Protein Biochemistry, National Research Council, 80131 Naples, Italy.
  • Di Marzo V; Institute of Biomolecular Chemistry, National Research Council, 80078 Pozzuoli, Italy;
  • Cristino L; Institute of Biomolecular Chemistry, National Research Council, 80078 Pozzuoli, Italy; luigia.cristino@icb.cnr.it.
Proc Natl Acad Sci U S A ; 113(17): 4759-64, 2016 Apr 26.
Article em En | MEDLINE | ID: mdl-27071101
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resposta de Saciedade / Pró-Opiomelanocortina / Alfa-MSH / Endocanabinoides / Orexinas / Neurônios / Obesidade Limite: Adult / Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resposta de Saciedade / Pró-Opiomelanocortina / Alfa-MSH / Endocanabinoides / Orexinas / Neurônios / Obesidade Limite: Adult / Animals / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article