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An Exposure-Response Modeling Approach to Examine the Relationship Between Potency of CYP3A Inducer and Plasma 4ß-Hydroxycholesterol in Healthy Subjects.
Jiang, Xuemin; Dutreix, Catherine; Jarugula, Venkateswar; Rebello, Sam; Won, Christina S; Sun, Haiying.
Afiliação
  • Jiang X; Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
  • Dutreix C; Oncology Clinical Pharmacology, Novartis Pharma AG, Basel, Switzerland.
  • Jarugula V; Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
  • Rebello S; Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
  • Won CS; Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
  • Sun H; Drug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, East Hanover, NJ, USA.
Clin Pharmacol Drug Dev ; 6(1): 19-26, 2017 Jan.
Article em En | MEDLINE | ID: mdl-27138546
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifampina / Indutores do Citocromo P-450 CYP3A / Hidroxicolesteróis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Pharmacol Drug Dev Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifampina / Indutores do Citocromo P-450 CYP3A / Hidroxicolesteróis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Pharmacol Drug Dev Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos