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Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures.
Wang, Xinchen; Tucker, Nathan R; Rizki, Gizem; Mills, Robert; Krijger, Peter Hl; de Wit, Elzo; Subramanian, Vidya; Bartell, Eric; Nguyen, Xinh-Xinh; Ye, Jiangchuan; Leyton-Mange, Jordan; Dolmatova, Elena V; van der Harst, Pim; de Laat, Wouter; Ellinor, Patrick T; Newton-Cheh, Christopher; Milan, David J; Kellis, Manolis; Boyer, Laurie A.
Afiliação
  • Wang X; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.
  • Tucker NR; Broad Institute of MIT and Harvard, Cambridge, United States.
  • Rizki G; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, United States.
  • Mills R; Cardiovascular Research Center, Massachusetts General Hospital, Boston, United States.
  • Krijger PH; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.
  • de Wit E; Cardiovascular Research Center, Massachusetts General Hospital, Boston, United States.
  • Subramanian V; Hubrecht Institute-KNAW, University Medical Center Utrecht, Utrecht, Netherlands.
  • Bartell E; University Medical Center Utrecht, Utrecht, Netherlands.
  • Nguyen XX; Hubrecht Institute-KNAW, University Medical Center Utrecht, Utrecht, Netherlands.
  • Ye J; University Medical Center Utrecht, Utrecht, Netherlands.
  • Leyton-Mange J; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.
  • Dolmatova EV; Department of Biology, Massachusetts Institute of Technology, Cambridge, United States.
  • van der Harst P; Cardiovascular Research Center, Massachusetts General Hospital, Boston, United States.
  • de Laat W; Cardiovascular Research Center, Massachusetts General Hospital, Boston, United States.
  • Ellinor PT; Cardiovascular Research Center, Massachusetts General Hospital, Boston, United States.
  • Newton-Cheh C; Cardiovascular Research Center, Massachusetts General Hospital, Boston, United States.
  • Milan DJ; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
  • Kellis M; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
  • Boyer LA; Hubrecht Institute-KNAW, University Medical Center Utrecht, Utrecht, Netherlands.
Elife ; 52016 05 10.
Article em En | MEDLINE | ID: mdl-27162171
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Loci Gênicos / Epigenômica / Sistema de Condução Cardíaco Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Loci Gênicos / Epigenômica / Sistema de Condução Cardíaco Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos