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HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Semba, Hiroaki; Takeda, Norihiko; Isagawa, Takayuki; Sugiura, Yuki; Honda, Kurara; Wake, Masaki; Miyazawa, Hidenobu; Yamaguchi, Yoshifumi; Miura, Masayuki; Jenkins, Dana M R; Choi, Hyunsung; Kim, Jung-Whan; Asagiri, Masataka; Cowburn, Andrew S; Abe, Hajime; Soma, Katsura; Koyama, Katsuhiro; Katoh, Manami; Sayama, Keimon; Goda, Nobuhito; Johnson, Randall S; Manabe, Ichiro; Nagai, Ryozo; Komuro, Issei.
Afiliação
  • Semba H; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Takeda N; Department of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo 106-0031, Japan.
  • Isagawa T; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Sugiura Y; PRESTO, JST, Saitama 332-0012, Japan.
  • Honda K; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Wake M; PRESTO, JST, Saitama 332-0012, Japan.
  • Miyazawa H; Department of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.
  • Yamaguchi Y; Department of Biochemistry, Keio University School of Medicine, Tokyo 160-8582, Japan.
  • Miura M; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Jenkins DM; Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-8655, Japan.
  • Choi H; PRESTO, JST, Saitama 332-0012, Japan.
  • Kim JW; Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-8655, Japan.
  • Asagiri M; Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-8655, Japan.
  • Cowburn AS; Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development, Tokyo 332-0012, Japan.
  • Abe H; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Soma K; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Koyama K; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, USA.
  • Katoh M; Innovation Center for Immunoregulation and Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
  • Sayama K; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 1SZ, UK.
  • Goda N; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Johnson RS; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Manabe I; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Nagai R; Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
  • Komuro I; Department of Life Science and Medical BioScience, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan.
Nat Commun ; 7: 11635, 2016 05 18.
Article em En | MEDLINE | ID: mdl-27189088
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Movimento Celular / Proteínas Serina-Treonina Quinases / Subunidade alfa do Fator 1 Induzível por Hipóxia / Glicólise / Macrófagos Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Movimento Celular / Proteínas Serina-Treonina Quinases / Subunidade alfa do Fator 1 Induzível por Hipóxia / Glicólise / Macrófagos Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Japão