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Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children.
Rautanen, Anna; Pirinen, Matti; Mills, Tara C; Rockett, Kirk A; Strange, Amy; Ndungu, Anne W; Naranbhai, Vivek; Gilchrist, James J; Bellenguez, Céline; Freeman, Colin; Band, Gavin; Bumpstead, Suzannah J; Edkins, Sarah; Giannoulatou, Eleni; Gray, Emma; Dronov, Serge; Hunt, Sarah E; Langford, Cordelia; Pearson, Richard D; Su, Zhan; Vukcevic, Damjan; Macharia, Alex W; Uyoga, Sophie; Ndila, Carolyne; Mturi, Neema; Njuguna, Patricia; Mohammed, Shebe; Berkley, James A; Mwangi, Isaiah; Mwarumba, Salim; Kitsao, Barnes S; Lowe, Brett S; Morpeth, Susan C; Khandwalla, Iqbal; Blackwell, Jenefer M; Bramon, Elvira; Brown, Matthew A; Casas, Juan P; Corvin, Aiden; Duncanson, Audrey; Jankowski, Janusz; Markus, Hugh S; Mathew, Christopher G; Palmer, Colin N A; Plomin, Robert; Sawcer, Stephen J; Trembath, Richard C; Viswanathan, Ananth C; Wood, Nicholas W; Deloukas, Panos.
Afiliação
  • Rautanen A; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. Electronic address: anna.rautanen@well.ox.ac.uk.
  • Pirinen M; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Mills TC; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Rockett KA; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Strange A; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Ndungu AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Naranbhai V; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Gilchrist JJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Department of Paediatrics, University of Oxford, Oxford OX3 9DU, UK.
  • Bellenguez C; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Freeman C; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Band G; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Bumpstead SJ; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Edkins S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Giannoulatou E; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Gray E; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Dronov S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Hunt SE; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Langford C; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Pearson RD; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Su Z; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Vukcevic D; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Macharia AW; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Uyoga S; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Ndila C; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Mturi N; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Njuguna P; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Mohammed S; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Berkley JA; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Mwangi I; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Mwarumba S; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Kitsao BS; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Lowe BS; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Morpeth SC; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya; Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 9DU, UK; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
  • Khandwalla I; KEMRI-Wellcome Trust Research Programme, Kilifi 80108, Kenya.
  • Blackwell JM; Cambridge Institute for Medical Research and Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK; Telethon Kids Institute, The University of Western Australia, Subiaco, WA 6008, Australia.
  • Bramon E; National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at the South London and Maudsley National Health Service (NHS) Foundation Trust and Institute of Psychiatry, King's College London, Denmark Hill, London SE5 8AF, UK.
  • Brown MA; Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Princess Alexandra Hospital, Brisbane, QLD 4102, Australia.
  • Casas JP; Farr Institute of Health Informatics, University College London, London NW1 2DA, UK.
  • Corvin A; Neuropsychiatric Genetics Research Group, Institute of Molecular Medicine, Trinity College Dublin, Dublin 2, Ireland.
  • Duncanson A; Molecular and Physiological Sciences, The Wellcome Trust, London NW1 2BE, UK.
  • Jankowski J; Associate Deans Office, John Bull Building, Peninsula School of Medicine and Dentistry, Plymouth PL6 8BU, UK.
  • Markus HS; Department of Neurology, University of Cambridge, Cambridge CB2 0QQ, UK.
  • Mathew CG; Division of Genetics and Molecular Medicine, King's College London, London SE1 9RT, UK; Sydney Brenner Institute for Molecular Bioscience, University of Witwatersrand, Johannesburg 2193, South Africa.
  • Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
  • Plomin R; MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK.
  • Sawcer SJ; Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
  • Trembath RC; London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
  • Viswanathan AC; NIHR Biomedical Research Centre at Moorfields Eye Hospital NHSFT and UCL Institute of Ophthalmology, London EC1V 2PD, UK.
  • Wood NW; Department of Molecular Neuroscience, Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Deloukas P; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Am J Hum Genet ; 98(6): 1092-1100, 2016 Jun 02.
Article em En | MEDLINE | ID: mdl-27236921
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Pneumocócica / Polimorfismo Genético / Streptococcus pneumoniae / Bacteriemia / RNA Longo não Codificante Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Newborn País/Região como assunto: Africa Idioma: En Revista: Am J Hum Genet Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Pneumocócica / Polimorfismo Genético / Streptococcus pneumoniae / Bacteriemia / RNA Longo não Codificante Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Newborn País/Região como assunto: Africa Idioma: En Revista: Am J Hum Genet Ano de publicação: 2016 Tipo de documento: Article