CD8 T-cell responses against the immunodominant Theileria parva peptide Tp249-59 are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes.

Connelley, Timothy K; Li, Xiaoying; MacHugh, Niall; Colau, Didier; Graham, Simon P; van der Bruggen, Pierre; Taracha, Evans L; Gill, Andy; Morrison, William Ivan

Connelley, Timothy K; Li, Xiaoying; MacHugh, Niall; Colau, Didier; Graham, Simon P; van der Bruggen, Pierre; Taracha, Evans L; Gill, Andy; Morrison, William Ivan.

Afiliação

Connelley TK; Division of Immunity and Infection, The Roslin Institute, The University of Edinburgh, Midlothian, UK.
Li X; Division of Immunity and Infection, The Roslin Institute, The University of Edinburgh, Midlothian, UK.
MacHugh N; Division of Immunity and Infection, The Roslin Institute, The University of Edinburgh, Midlothian, UK.
Colau D; Ludwig Institute for Cancer Research and de Duve Institute, Universite catholique de Louvain, Brussels, Belgium.
Graham SP; The International Livestock Research Institute, Nairobi, Kenya.
van der Bruggen P; Ludwig Institute for Cancer Research and de Duve Institute, Universite catholique de Louvain, Brussels, Belgium.
Taracha EL; The International Livestock Research Institute, Nairobi, Kenya.
Gill A; Division of Neurobiology, The Roslin Institute, The University of Edinburgh, Midlothian, UK.
Morrison WI; Division of Immunity and Infection, The Roslin Institute, The University of Edinburgh, Midlothian, UK.

Immunology ; 149(2): 172-85, 2016 10.

Article em En | MEDLINE | ID: mdl-27317384

Assuntos

Linfócitos T CD8-Positivos/imunologia; Vacinas Protozoárias/imunologia; Subpopulações de Linfócitos T/imunologia; Theileria parva/imunologia; Theileriose/imunologia; Animais; Antígenos de Protozoários/metabolismo; Bovinos; Linhagem Celular; Simulação por Computador; Mapeamento de Epitopos; Epitopos de Linfócito T/metabolismo; Antígenos de Histocompatibilidade Classe I/metabolismo; Epitopos Imunodominantes/metabolismo; Ativação Linfocitária; Fragmentos de Peptídeos/metabolismo; Ligação Proteica

Palavras-chave

CD8 T cell; Theileria parva; cattle; epitope; tetramer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Theileriose / Subpopulações de Linfócitos T / Vacinas Protozoárias / Theileria parva / Linfócitos T CD8-Positivos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Immunology Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido

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