[Multiparametric and molecular imaging of breast tumors with MRI and PET/MRI]. / Multiparametrische und molekulare Bildgebung von Brusttumoren mit MRT und PETMRT.
Radiologe
; 56(7): 612-21, 2016 Jul.
Article
em De
| MEDLINE
| ID: mdl-27364727
ABSTRACT
CLINICAL/METHODICAL ISSUE Magnetic resonance imaging (MRI) of the breast is an indispensable tool in breast imaging for many indications. Several functional parameters with MRI and positron emission tomography (PET) have been assessed for imaging of breast tumors and their combined application is defined as multiparametric imaging. Available data suggest that multiparametric imaging using different functional MRI and PET parameters can provide detailed information about the hallmarks of cancer and may provide additional specificity. STANDARD RADIOLOGICAL METHODS:
Multiparametric and molecular imaging of the breast comprises established MRI parameters, such as dynamic contrast-enhanced MRI, diffusion-weighted imaging (DWI), MR proton spectroscopy ((1)H-MRSI) as well as combinations of radiological and MRI techniques (e. g. PET/CT and PET/MRI) using radiotracers, such as fluorodeoxyglucose (FDG). METHODICAL INNOVATIONS Multiparametric and molecular imaging of the breast can be performed at different field-strengths (range 1.5-7 T). Emerging parameters comprise novel promising techniques, such as sodium imaging ((23)Na MRI), phosphorus spectroscopy ((31)P-MRSI), chemical exchange saturation transfer (CEST) imaging, blood oxygen level-dependent (BOLD) and hyperpolarized MRI as well as various specific radiotracers. ACHIEVEMENTS Multiparametric and molecular imaging has multiple applications in breast imaging. Multiparametric and molecular imaging of the breast is an evolving field that will enable improved detection, characterization, staging and monitoring for personalized medicine in breast cancer.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
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Imageamento por Ressonância Magnética
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Compostos Radiofarmacêuticos
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Tomografia por Emissão de Pósitrons
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Imagem Molecular
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Imagem Multimodal
Tipo de estudo:
Diagnostic_studies
Limite:
Female
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Humans
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Male
Idioma:
De
Revista:
Radiologe
Ano de publicação:
2016
Tipo de documento:
Article