Your browser doesn't support javascript.
loading
An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression.
Wyszynski, Asaf; Hong, Chi-Chen; Lam, Kristin; Michailidou, Kyriaki; Lytle, Christian; Yao, Song; Zhang, Yali; Bolla, Manjeet K; Wang, Qin; Dennis, Joe; Hopper, John L; Southey, Melissa C; Schmidt, Marjanka K; Broeks, Annegien; Muir, Kenneth; Lophatananon, Artitaya; Fasching, Peter A; Beckmann, Matthias W; Peto, Julian; Dos-Santos-Silva, Isabel; Sawyer, Elinor J; Tomlinson, Ian; Burwinkel, Barbara; Marme, Frederik; Guénel, Pascal; Truong, Thérèse; Bojesen, Stig E; Nordestgaard, Børge G; González-Neira, Anna; Benitez, Javier; Neuhausen, Susan L; Brenner, Hermann; Dieffenbach, Aida Karina; Meindl, Alfons; Schmutzler, Rita K; Brauch, Hiltrud; Nevanlinna, Heli; Khan, Sofia; Matsuo, Keitaro; Ito, Hidemi; Dörk, Thilo; Bogdanova, Natalia V; Lindblom, Annika; Margolin, Sara; Mannermaa, Arto; Kosma, Veli-Matti; Wu, Anna H; Van Den Berg, David; Lambrechts, Diether; Wildiers, Hans.
Afiliação
  • Wyszynski A; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
  • Hong CC; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
  • Lam K; Dartmouth College, Hanover, NH 03755 USA.
  • Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Lytle C; Molecular Biology Core Facility, Dartmouth College, Hanover, NH 03755 USA.
  • Yao S; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
  • Zhang Y; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
  • Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Wang Q; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Dennis J; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia.
  • Southey MC; Department of Pathology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
  • Schmidt MK; Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, 1066 CX Amsterdam, The Netherlands.
  • Broeks A; Wellcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, OX3 7BN, UK.
  • Muir K; Division of Health Sciences, Warwick Medical school, Warwick University, Coventry, CV4 7AL, UK.
  • Lophatananon A; Institute of Population Health, University of Manchester, Manchester, M13 9PL, UK.
  • Fasching PA; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Beckmann MW; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
  • Peto J; David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA 90095, USA.
  • Dos-Santos-Silva I; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
  • Sawyer EJ; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
  • Tomlinson I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK.
  • Burwinkel B; Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital, London, SE1 9RT, UK.
  • Marme F; Wellcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford, OX3 7BN, UK.
  • Guénel P; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Truong T; Molecular Epidemiology Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Bojesen SE; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.
  • Nordestgaard BG; National Center for Tumor Diseases, University of Heidelberg, 69120 Heidelberg, Germany.
  • González-Neira A; Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 94807 Villejuif, France.
  • Benitez J; University Paris-Sud, UMRS 1018, 94807 Villejuif, France.
  • Neuhausen SL; Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 94807 Villejuif, France.
  • Brenner H; University Paris-Sud, UMRS 1018, 94807 Villejuif, France.
  • Dieffenbach AK; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.
  • Meindl A; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.
  • Schmutzler RK; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.
  • Brauch H; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark.
  • Nevanlinna H; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.
  • Khan S; Centro de Investigación en Red de Enfermedades Raras (CIBERER), 46010 Valencia, Spain.
  • Matsuo K; Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
  • Ito H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Dörk T; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.
  • Bogdanova NV; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Lindblom A; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.
  • Margolin S; Division of Gynaecology and Obstetrics, Technische Universität München, 81675 Munich, Germany.
  • Mannermaa A; Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, University Hospital of Cologne, 50931 Cologne, Germany.
  • Kosma VM; Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, 50931 Cologne, Germany.
  • Wu AH; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.
  • Van Den Berg D; University of Tübingen, 72074 Tübingen, Germany.
  • Wildiers H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, FI-00029 HUS, Finland.
Hum Mol Genet ; 25(17): 3863-3876, 2016 09 01.
Article em En | MEDLINE | ID: mdl-27402876
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 2 / Neoplasias da Mama / Proteínas de Transporte / Elementos Facilitadores Genéticos / Deleção de Sequência / Proteína 5 de Ligação a Fator de Crescimento Semelhante à Insulina Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 2 / Neoplasias da Mama / Proteínas de Transporte / Elementos Facilitadores Genéticos / Deleção de Sequência / Proteína 5 de Ligação a Fator de Crescimento Semelhante à Insulina Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos