Two-Mechanism Model for the Interaction of Etoposide Quinone with Topoisomerase II&#945;.

Gibson, Elizabeth G; King, McKenzie M; Mercer, Susan L; Deweese, Joseph E

Two-Mechanism Model for the Interaction of Etoposide Quinone with Topoisomerase IIα.

Gibson, Elizabeth G; King, McKenzie M; Mercer, Susan L; Deweese, Joseph E.

Afiliação

Gibson EG; Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy and Health Sciences , One University Park Drive, Nashville, Tennessee 37204-3951, United States.
King MM; Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy and Health Sciences , One University Park Drive, Nashville, Tennessee 37204-3951, United States.
Mercer SL; Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy and Health Sciences , One University Park Drive, Nashville, Tennessee 37204-3951, United States.
Deweese JE; Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy and Health Sciences , One University Park Drive, Nashville, Tennessee 37204-3951, United States.

Chem Res Toxicol ; 29(9): 1541-8, 2016 09 19.

Article em En | MEDLINE | ID: mdl-27533850

Assuntos

Antígenos de Neoplasias/metabolismo; DNA Topoisomerases Tipo II/metabolismo; Proteínas de Ligação a DNA/metabolismo; Modelos Biológicos; Quinonas/metabolismo; Sítios de Ligação/efeitos dos fármacos; Etoposídeo/química; Etoposídeo/metabolismo; Etoposídeo/farmacologia; Humanos; Estrutura Molecular; Quinonas/química; Quinonas/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinonas / DNA Topoisomerases Tipo II / Proteínas de Ligação a DNA / Modelos Biológicos / Antígenos de Neoplasias Limite: Humans Idioma: En Revista: Chem Res Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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