Lymphocyte ecto-5'-nucleotidase deficiency in agammaglobulinemia.
Science
; 201(4356): 628-30, 1978 Aug 18.
Article
em En
| MEDLINE
| ID: mdl-27864
ABSTRACT
Fresh peripheral blood lymphocytes from eight patients with congenital agammaglobulinemia demonstrate reduced ecto-5'-nucleotidase activity when compared to the mean activity of normal subjects and patients with other forms of immunoglobulin deficiency. A specific defect of ecto-5'-nucleotidase is further suggested by normal values for lymphocyte ecto-adenosinetriphosphatase and ecto-nonspecific phosphatase. The data provide evidence for an enzyme deficiency in this X-linked, B lymphocyte deficiency syndrome.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos
/
Agamaglobulinemia
/
Nucleotidases
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Science
Ano de publicação:
1978
Tipo de documento:
Article