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Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer.
Liow, Sing Shy; Dou, Qingqing; Kai, Dan; Li, Zibiao; Sugiarto, Sigit; Yu, Chris Yee Yung; Kwok, Ryan Tsz Kin; Chen, Xiaohong; Wu, Yun-Long; Ong, Seow Theng; Kizhakeyil, Atish; Verma, Navin K; Tang, Ben Zhong; Loh, Xian Jun.
Afiliação
  • Liow SS; Institute of Materials Research and Engineering (IMRE), 2 Fusionopolis Way, #08-03 Innovis, Singapore, 138634, Singapore.
  • Dou Q; Institute of Materials Research and Engineering (IMRE), 2 Fusionopolis Way, #08-03 Innovis, Singapore, 138634, Singapore.
  • Kai D; Institute of Materials Research and Engineering (IMRE), 2 Fusionopolis Way, #08-03 Innovis, Singapore, 138634, Singapore.
  • Li Z; Institute of Materials Research and Engineering (IMRE), 2 Fusionopolis Way, #08-03 Innovis, Singapore, 138634, Singapore.
  • Sugiarto S; Institute of Materials Research and Engineering (IMRE), 2 Fusionopolis Way, #08-03 Innovis, Singapore, 138634, Singapore.
  • Yu CY; Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, 999077, China.
  • Kwok RT; Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, 999077, China.
  • Chen X; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, 361102, P. R. China.
  • Wu YL; Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, 361102, P. R. China.
  • Ong ST; Lee Kong Chian School of Medicine, Nanyang Technological University, Experimental Medicine Building, Singapore, 636921, Singapore.
  • Kizhakeyil A; Lee Kong Chian School of Medicine, Nanyang Technological University, Experimental Medicine Building, Singapore, 636921, Singapore.
  • Verma NK; Lee Kong Chian School of Medicine, Nanyang Technological University, Experimental Medicine Building, Singapore, 636921, Singapore.
  • Tang BZ; Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, 999077, China.
  • Loh XJ; Institute of Materials Research and Engineering (IMRE), 2 Fusionopolis Way, #08-03 Innovis, Singapore, 138634, Singapore.
Small ; 13(7)2017 02.
Article em En | MEDLINE | ID: mdl-27930860
A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion of drugs, and reinject to maintain a dosage in the optimal therapeutic window.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Temperatura / Sistemas Computacionais / Liberação Controlada de Fármacos / Géis Limite: Animals / Humans Idioma: En Revista: Small Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Singapura
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Temperatura / Sistemas Computacionais / Liberação Controlada de Fármacos / Géis Limite: Animals / Humans Idioma: En Revista: Small Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Singapura