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Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells.
Song, Juan; Cano-Rodriquez, David; Winkle, Melanie; Gjaltema, Rutger A F; Goubert, Désirée; Jurkowski, Tomasz P; Heijink, Irene H; Rots, Marianne G; Hylkema, Machteld N.
Afiliação
  • Song J; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.
  • Cano-Rodriquez D; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands.
  • Winkle M; Tianjin Medical University, School of Basic Medical Sciences, Department of Biochemistry and Molecular Biology, Department of Immunology, Tianjin, China; and.
  • Gjaltema RA; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.
  • Goubert D; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.
  • Jurkowski TP; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.
  • Heijink IH; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.
  • Rots MG; Institute of Biochemistry, Faculty of Chemistry, University of Stuttgart, Stuttgart, Germany.
  • Hylkema MN; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands.
Am J Physiol Lung Cell Mol Physiol ; 312(3): L334-L347, 2017 03 01.
Article em En | MEDLINE | ID: mdl-28011616
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epigênese Genética / Células Epiteliais / Proteínas Proto-Oncogênicas c-ets / Edição de Genes / Pulmão / Muco Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epigênese Genética / Células Epiteliais / Proteínas Proto-Oncogênicas c-ets / Edição de Genes / Pulmão / Muco Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda