Multiresolution imaging using golden angle stack-of-stars and compressed sensing for dynamic MR urography.
J Magn Reson Imaging
; 46(1): 303-311, 2017 07.
Article
em En
| MEDLINE
| ID: mdl-28176396
ABSTRACT
PURPOSE:
To develop a novel multiresolution MRI methodology for accurate estimation of glomerular filtration rate (GFR) in vivo. MATERIALS ANDMETHODS:
A three-dimensional golden-angle radial stack-of-stars (SoS) trajectory was used for data acquisition on a 3 Tesla MRI scanner. Multiresolution reconstruction and analysis was performed using arterial input function reconstructed at 1-s. temporal resolution and renal dynamic data reconstructed using compressed sensing (CS) with 4-s temporal resolution. The method was first validated using simulations and the clinical utility of the technique was evaluated by comparing the GFR estimates from the proposed method to the estimated GFR (eGFR) obtained from serum creatinine for 10 subjects.RESULTS:
The 4-s temporal resolution CS images minimized streaking artifacts and noise while the 1-s temporal resolution AIF minimized errors in GFR estimates. A paired t-test showed that there was no statistically significant difference between MRI based total GFR values and serum creatinine based eGFR estimates (P = 0.92).CONCLUSION:
We have demonstrated the feasibility of multiresolution MRI using a golden angle radial stack-of-stars scheme to accurately estimate GFR as well as produce diagnostic quality dynamic images in vivo. LEVEL OF EVIDENCE 1 Technical Efficacy Stage 3 J. MAGN. RESON. IMAGING 2017;46303-311.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Processamento de Sinais Assistido por Computador
/
Imageamento por Ressonância Magnética
/
Compressão de Dados
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Taxa de Filtração Glomerular
/
Rim
/
Testes de Função Renal
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
J Magn Reson Imaging
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos