Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [<sup>11</sup>C]PBR28.

Collste, K; Plavén-Sigray, P; Fatouros-Bergman, H; Victorsson, P; Schain, M; Forsberg, A; Amini, N; Aeinehband, S; Erhardt, S; Halldin, C; Flyckt, L; Farde, L; Cervenka, S

Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [¹¹C]PBR28.

Collste, K; Plavén-Sigray, P; Fatouros-Bergman, H; Victorsson, P; Schain, M; Forsberg, A; Amini, N; Aeinehband, S; Erhardt, S; Halldin, C; Flyckt, L; Farde, L; Cervenka, S.

Afiliação

Collste K; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Plavén-Sigray P; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Fatouros-Bergman H; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Victorsson P; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Schain M; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Forsberg A; Molecular Imaging and Neuropathology Division, Department of Psychiatry, Columbia University, New York, NY, USA.
Amini N; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Aeinehband S; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Halldin C; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Flyckt L; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Farde L; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
Cervenka S; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.

Mol Psychiatry ; 22(6): 850-856, 2017 06.

Article em En | MEDLINE | ID: mdl-28194003

Assuntos

Neuroglia/química; Transtornos Psicóticos/diagnóstico por imagem; Receptores de GABA/análise; Esquizofrenia/metabolismo; Acetamidas; Adulto; Biomarcadores/metabolismo; Encéfalo/diagnóstico por imagem; Encéfalo/metabolismo; Radioisótopos de Carbono; Estudos de Casos e Controles; Feminino; Substância Cinzenta/diagnóstico por imagem; Substância Cinzenta/microbiologia; Humanos; Masculino; Microglia/metabolismo; Neuroglia/metabolismo; Neuroglia/patologia; Tomografia por Emissão de Pósitrons/métodos; Piridinas; Ensaio Radioligante; Compostos Radiofarmacêuticos; Receptores de GABA/metabolismo; Esquizofrenia/diagnóstico por imagem; Esquizofrenia/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Psicóticos / Esquizofrenia / Neuroglia / Receptores de GABA Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Mol Psychiatry Assunto da revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia

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