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The discovery of fluazaindolizine: A new product for the control of plant parasitic nematodes.
Lahm, George P; Desaeger, Johan; Smith, Ben K; Pahutski, Thomas F; Rivera, Michel A; Meloro, Tony; Kucharczyk, Roman; Lett, Renee M; Daly, Anne; Smith, Brenton T; Cordova, Daniel; Thoden, Tim; Wiles, John A.
Afiliação
  • Lahm GP; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA. Electronic address: george.p.lahm@dupont.com.
  • Desaeger J; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Smith BK; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Pahutski TF; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Rivera MA; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Meloro T; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Kucharczyk R; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Lett RM; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Daly A; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Smith BT; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Cordova D; DuPont Crop Protection, Stine-Haskell Research Center, 1090 Elkton Rd., Newark, DE 19714, USA.
  • Thoden T; DuPont de Nemours (France) S.A.S., European Research Center, 68740 Nambsheim, France.
  • Wiles JA; DuPont (U.K.) Limited, 4th Floor, Kings Court, London Road, Stevenage SG1 2NG, United Kingdom.
Bioorg Med Chem Lett ; 27(7): 1572-1575, 2017 04 01.
Article em En | MEDLINE | ID: mdl-28242274
ABSTRACT
Fluazaindolizine is a new highly effective and selective product for the control of plant parasitic nematodes. Specificity for nematodes coupled with absence of activity against the target sites of commercial nematicides suggests that fluazaindolizine has a novel mode of action. The discovery, structure-activity development and biological properties for this new class of nematicides are presented.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Praguicidas / Sulfonamidas / Compostos Heterocíclicos com 2 Anéis / Indolizinas Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Praguicidas / Sulfonamidas / Compostos Heterocíclicos com 2 Anéis / Indolizinas Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article