Kinetic-based trapping by intervening sequence variants of the active sites of protein-disulfide isomerase identifies platelet protein substrates.

Stopa, Jack D; Baker, Katherine M; Grover, Steven P; Flaumenhaft, Robert; Furie, Bruce

Stopa, Jack D; Baker, Katherine M; Grover, Steven P; Flaumenhaft, Robert; Furie, Bruce.

Afiliação

Stopa JD; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215.
Baker KM; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215.
Grover SP; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215.
Flaumenhaft R; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215.
Furie B; From the Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215 bfurie@bidmc.harvard.edu.

J Biol Chem ; 292(22): 9063-9074, 2017 06 02.

Article em En | MEDLINE | ID: mdl-28364042

Assuntos

Plaquetas/enzimologia; Isomerases de Dissulfetos de Proteínas/química; Domínio Catalítico; Humanos; Cinética; Isomerases de Dissulfetos de Proteínas/metabolismo; Especificidade por Substrato

Palavras-chave

disulfide; oxidase; platelet; protein disulfide isomerase; protein-protein interaction; reductase

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plaquetas / Isomerases de Dissulfetos de Proteínas Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google