M2-like macrophage polarization in high lactic acid-producing head and neck cancer.

Ohashi, Toshimitsu; Aoki, Mitsuhiro; Tomita, Hiroyuki; Akazawa, Takashi; Sato, Katsuya; Kuze, Bunya; Mizuta, Keisuke; Hara, Akira; Nagaoka, Hitoshi; Inoue, Norimitsu; Ito, Yatsuji

Ohashi, Toshimitsu; Aoki, Mitsuhiro; Tomita, Hiroyuki; Akazawa, Takashi; Sato, Katsuya; Kuze, Bunya; Mizuta, Keisuke; Hara, Akira; Nagaoka, Hitoshi; Inoue, Norimitsu; Ito, Yatsuji.

Afiliação

Ohashi T; Department of Otolaryngology, Gifu University Graduate School of Medicine, Gifu, Japan.
Aoki M; Department of Otolaryngology, Gifu University Graduate School of Medicine, Gifu, Japan.
Tomita H; Department of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu, Japan.
Akazawa T; Department of Tumor Immunology, Osaka International Cancer Institute, Osaka, Japan.
Sato K; Department of Molecular Pathobiochemistry, Gifu University Graduate School of Medicine, Gifu, Japan.
Kuze B; Department of Otolaryngology, Gifu University Graduate School of Medicine, Gifu, Japan.
Mizuta K; Department of Otolaryngology, Gifu University Graduate School of Medicine, Gifu, Japan.
Hara A; Department of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu, Japan.
Nagaoka H; Department of Molecular Pathobiochemistry, Gifu University Graduate School of Medicine, Gifu, Japan.
Inoue N; Department of Tumor Immunology, Osaka International Cancer Institute, Osaka, Japan.
Ito Y; Department of Otolaryngology, Gifu University Graduate School of Medicine, Gifu, Japan.

Cancer Sci ; 108(6): 1128-1134, 2017 Jun.

Article em En | MEDLINE | ID: mdl-28370718

Assuntos

Neoplasias de Cabeça e Pescoço/metabolismo; Neoplasias de Cabeça e Pescoço/patologia; Ácido Láctico/metabolismo; Macrófagos/patologia; Antígenos CD/metabolismo; Antígenos de Diferenciação Mielomonocítica/metabolismo; Biomarcadores Tumorais/metabolismo; Carcinoma de Células Escamosas/metabolismo; Carcinoma de Células Escamosas/patologia; Linhagem Celular Tumoral; Humanos; Macrófagos/metabolismo; Receptores de Superfície Celular/metabolismo; Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos/metabolismo; Carcinoma de Células Escamosas de Cabeça e Pescoço

Palavras-chave

Head and neck squamous cell carcinoma; Warburg effect; lactic acid; macrophage polarization; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Láctico / Neoplasias de Cabeça e Pescoço / Macrófagos Limite: Humans Idioma: En Revista: Cancer Sci Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão

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