Complete deletion of <i>Cd39</i> is atheroprotective in apolipoprotein E-deficient mice.

De Giorgi, Marco; Enjyoji, Keiichi; Jiang, Gordon; Csizmadia, Eva; Mitsuhashi, Shuji; Gumina, Richard J; Smolenski, Ryszard T; Robson, Simon C

Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice.

De Giorgi, Marco; Enjyoji, Keiichi; Jiang, Gordon; Csizmadia, Eva; Mitsuhashi, Shuji; Gumina, Richard J; Smolenski, Ryszard T; Robson, Simon C.

Afiliação

De Giorgi M; Transplant Institute and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Enjyoji K; Transplant Institute and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Jiang G; Transplant Institute and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Csizmadia E; Transplant Institute and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Mitsuhashi S; Transplant Institute and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Gumina RJ; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Smolenski RT; Department of Biochemistry, Medical University of Gdansk, Gdansk, Poland.
Robson SC; Transplant Institute and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA. Electronic address: srobson@bidmc.harvard.edu.

J Lipid Res ; 58(7): 1292-1305, 2017 07.

Article em En | MEDLINE | ID: mdl-28487312

Assuntos

Antígenos CD/genética; Apolipoproteínas E/deficiência; Apirase/deficiência; Apirase/genética; Aterosclerose/genética; Técnicas de Inativação de Genes; Animais; Aterosclerose/metabolismo; Aterosclerose/patologia; Aterosclerose/fisiopatologia; Transporte Biológico/genética; Movimento Celular/genética; Proliferação de Células/genética; Colesterol/metabolismo; Macrófagos/metabolismo; Masculino; Camundongos; Músculo Liso Vascular/patologia; Necrose/genética; Fenótipo; Ativação Plaquetária/genética

Palavras-chave

adenosine 5'-triphosphate; atherosclerosis; cholesterol/efflux; cluster of differentiation 39; foam cells; macrophages; platelets; vascular biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas E / Apirase / Antígenos CD / Aterosclerose / Técnicas de Inativação de Genes Limite: Animals Idioma: En Revista: J Lipid Res Ano de publicação: 2017 Tipo de documento: Article

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