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Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1.
Mould, Daniel P; Bremberg, Ulf; Jordan, Allan M; Geitmann, Matthis; Maiques-Diaz, Alba; McGonagle, Alison E; Small, Helen F; Somervaille, Tim C P; Ogilvie, Donald.
Afiliação
  • Mould DP; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address: daniel.mould@cruk.manchester.ac.uk.
  • Bremberg U; Beactica AB, Uppsala Business Park, Virdings allé 2, 75450, Uppsala, Sweden.
  • Jordan AM; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.
  • Geitmann M; Beactica AB, Uppsala Business Park, Virdings allé 2, 75450, Uppsala, Sweden.
  • Maiques-Diaz A; Leukaemia Biology Group, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.
  • McGonagle AE; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.
  • Small HF; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.
  • Somervaille TCP; Leukaemia Biology Group, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.
  • Ogilvie D; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.
Bioorg Med Chem Lett ; 27(14): 3190-3195, 2017 07 15.
Article em En | MEDLINE | ID: mdl-28545974
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Histona Desmetilases Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Histona Desmetilases Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article