Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling.

Lambert, William D; Scinto, Samuel L; Dmitrenko, Olga; Boyd, Samantha J; Magboo, Ronald; Mehl, Ryan A; Chin, Jason W; Fox, Joseph M; Wallace, Stephen

Lambert, William D; Scinto, Samuel L; Dmitrenko, Olga; Boyd, Samantha J; Magboo, Ronald; Mehl, Ryan A; Chin, Jason W; Fox, Joseph M; Wallace, Stephen.

Afiliação

Lambert WD; Brown Laboratory, Department of Chemistry & Biochemistry, University of Delaware, Newark, Delaware 19716, USA. jmfox@udel.edu.
Scinto SL; Brown Laboratory, Department of Chemistry & Biochemistry, University of Delaware, Newark, Delaware 19716, USA. jmfox@udel.edu.
Dmitrenko O; Brown Laboratory, Department of Chemistry & Biochemistry, University of Delaware, Newark, Delaware 19716, USA. jmfox@udel.edu.
Boyd SJ; Brown Laboratory, Department of Chemistry & Biochemistry, University of Delaware, Newark, Delaware 19716, USA. jmfox@udel.edu.
Magboo R; Lotus Separations LLC, Newark, DE 19711, USA.
Mehl RA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, USA.
Chin JW; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.
Fox JM; Brown Laboratory, Department of Chemistry & Biochemistry, University of Delaware, Newark, Delaware 19716, USA. jmfox@udel.edu.
Wallace S; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK and Institute of Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh, UK.

Org Biomol Chem ; 15(31): 6640-6644, 2017 Aug 09.

Article em En | MEDLINE | ID: mdl-28752889

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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