Balanochalcone, a new chalcone from Balanophora laxiflora Hemsl.
Nat Prod Res
; 32(7): 767-772, 2018 Apr.
Article
em En
| MEDLINE
| ID: mdl-28778140
ABSTRACT
A new chalcone named as balanochalcone (1) together with eight known compounds, methyl caffeate (2), ß-hydroxydihydrochalcone (3), methyl gallate (4), dimethyl-6,9,10-trihydroxybenzo[kl]xanthene-1,2-dicarboxylate (5), p-coumaric acid (6), quercetin (7), scopoletin (8) and pinoresinol (9) have been isolated from the ethyl acetate extract of Vietnamese Balanophora laxiflora Hemsl. Their structures were characterised by IR, UV, HR-ESI-MS, 1D and 2D NMR and CD spectroscopies. Compounds 2 and 5 showed moderate cytotoxicity against four cancer cell lines, KB (a human epidermal carcinoma), MCF7 (human breast carcinoma), SK-LU-1 (human lung carcinoma) and HepG2 (hepatocellular carcinoma). In addition, compounds 1 and 5 showed moderate antioxidant activity.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Santalaceae
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Chalconas
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Antineoplásicos Fitogênicos
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Antioxidantes
Limite:
Humans
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Vietnã