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Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling.
Andersson, E I; Pützer, S; Yadav, B; Dufva, O; Khan, S; He, L; Sellner, L; Schrader, A; Crispatzu, G; Oles, M; Zhang, H; Adnan-Awad, S; Lagström, S; Bellanger, D; Mpindi, J P; Eldfors, S; Pemovska, T; Pietarinen, P; Lauhio, A; Tomska, K; Cuesta-Mateos, C; Faber, E; Koschmieder, S; Brümmendorf, T H; Kytölä, S; Savolainen, E-R; Siitonen, T; Ellonen, P; Kallioniemi, O; Wennerberg, K; Ding, W; Stern, M-H; Huber, W; Anders, S; Tang, J; Aittokallio, T; Zenz, T; Herling, M; Mustjoki, S.
Afiliação
  • Andersson EI; Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • Pützer S; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), CMMC, Center for Molecular Medicine, University of Cologne, Germany.
  • Yadav B; Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • Dufva O; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Khan S; Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • He L; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Sellner L; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Schrader A; Department of Translational Oncology and Molecular Therapy in Haematology and Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany.
  • Crispatzu G; Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany.
  • Oles M; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), CMMC, Center for Molecular Medicine, University of Cologne, Germany.
  • Zhang H; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, Excellence Cluster for Cellular Stress Response and Aging-Associated Diseases (CECAD), CMMC, Center for Molecular Medicine, University of Cologne, Germany.
  • Adnan-Awad S; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
  • Lagström S; Division of Hematology, Mayo Clinic, Rochester, MN, USA.
  • Bellanger D; Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • Mpindi JP; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Eldfors S; Institut Curie, INSERM U830, PSL Research University, Paris, France.
  • Pemovska T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Pietarinen P; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Lauhio A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Tomska K; Hematology Research Unit Helsinki, Department of Clinical Chemistry and Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
  • Cuesta-Mateos C; Department of Medicine, Division of Infectious Disease, Helsinki University Central Hospital (HUCH), Helsinki, Finland.
  • Faber E; Department of Translational Oncology and Molecular Therapy in Haematology and Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany.
  • Koschmieder S; Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany.
  • Brümmendorf TH; Departamento de Immunología, Hospital Universitario de la Princesa, Madrid, Spain.
  • Kytölä S; Department of Hemato-oncology, University Hospital Olomouc, Olomouc, Czech Republic.
  • Savolainen ER; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Siitonen T; Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Ellonen P; Helsinki University Central Hospital (HUCH), Laboratory of Genetics, HUSLAB, Helsinki, Finland.
  • Kallioniemi O; Nordlab Oulu, Hematology Laboratory, MRC Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland.
  • Wennerberg K; Department of Hematology, Oulu University Hospital, MRC Oulu, University of Oulu, Oulu, Finland.
  • Ding W; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Stern MH; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Huber W; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Anders S; Division of Hematology, Mayo Clinic, Rochester, MN, USA.
  • Tang J; Institut Curie, INSERM U830, PSL Research University, Paris, France.
  • Aittokallio T; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
  • Zenz T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Herling M; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Mustjoki S; Department of Mathematics and Statistics, University of Turku, Turku, Finland.
Leukemia ; 32(3): 774-787, 2018 03.
Article em En | MEDLINE | ID: mdl-28804127
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ensaios de Seleção de Medicamentos Antitumorais / Leucemia Prolinfocítica de Células T / Biomarcadores Tumorais / Resistencia a Medicamentos Antineoplásicos / Ensaios de Triagem em Larga Escala / Mutação / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ensaios de Seleção de Medicamentos Antitumorais / Leucemia Prolinfocítica de Células T / Biomarcadores Tumorais / Resistencia a Medicamentos Antineoplásicos / Ensaios de Triagem em Larga Escala / Mutação / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Finlândia