Editorial: Severe Acute Liver Injury: Cause Connects to Outcome.
Am J Gastroenterol
; 112(9): 1397-1399, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28874859
ABSTRACT
Severe acute liver injury (ALI) is a common condition with little objective study of its natural history and outcomes. In this paper by Koch et al. and the Acute Liver Failure (ALF) Study Group, the authors utilize a consensus definition of ALI requiring newly elevated bilirubin, alanine aminotransferase (ALT), and international normalized ration (INR) without evidence of hepatic encephalopathy (HE), with HE as the key differentiator of ALI from ALF. They show significantly higher rates of progression to ALF, liver transplantation, or death in non-acetaminophen etiologies of ALI. This study's findings provide guidance in supporting careful allocation of scarce critical care and liver transplant resources for ALI patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Fígado
/
Doença Hepática Induzida por Substâncias e Drogas
Tipo de estudo:
Etiology_studies
/
Guideline
Limite:
Humans
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Am J Gastroenterol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos