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Outbreaks of epidemic keratoconjunctivitis caused by human adenovirus type 8 in the Tibet Autonomous Region of China in 2016.
Lei, Zhenqiang; Zhu, Zhen; Wang, Bai Ma Ci; Mei, Hong; Li, Hong; Ga, Dan Zeng Gong; Jie, Guo; Chi, Mi Ma Bu; Zhang, Sheng; Ma, Chaofeng; Xu, Wenbo.
Afiliação
  • Lei Z; School of Public Health, Shaanxi University of Chinese Medicine, Xianyang city, Shaanxi province, People's Republic of China.
  • Zhu Z; WHO WPRO Regional Reference Measles/Rubella laboratory and Key Laboratory of Medical Virology Ministry of Health, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing City, People's Republic of China.
  • Wang BMC; Department of Infectious Diseases, Tibet Center for Disease Control and Prevention, Lhasa city, Tibet Autonomous Region, People's Republic of China.
  • Mei H; Department of Health Inspection, Tibet Center for Disease Control and Prevention, Lhasa city, Tibet Autonomous Region, People's Republic of China.
  • Li H; Department of Pathogenic Biology, Medical School, Anhui University of Science and Technology, Huainan City, Anhui Province, People's Republic of China.
  • Ga DZG; Department of Infectious Diseases, Tibet Center for Disease Control and Prevention, Lhasa city, Tibet Autonomous Region, People's Republic of China.
  • Jie G; Gongbujiangda County Center for Disease Control and Prevention, Linzhi City, Tibet Autonomous Region, People's Republic of China.
  • Chi MMB; Department of Infectious Diseases, Rikaze Prefecture Center for Disease Control and Prevention, Rikaze City, Tibet Autonomous Region, People's Republic of China.
  • Zhang S; WHO WPRO Regional Reference Measles/Rubella laboratory and Key Laboratory of Medical Virology Ministry of Health, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing City, People's Republic of China.
  • Ma C; School of Public Health, Shaanxi University of Chinese Medicine, Xianyang city, Shaanxi province, People's Republic of China.
  • Xu W; Xi'an Center for Disease Control and Prevention, Xi'an City, Shaanxi Province, People's Republic of China.
PLoS One ; 12(9): e0185048, 2017.
Article em En | MEDLINE | ID: mdl-28915257
From April to November 2016, two outbreaks of epidemic keratoconjunctivitis (EKC) occurred successively at primary and middle schools in the Tibet Autonomous Region of China, and a total of 197 clinically diagnosed cases were reported. Real-time PCR analyses confirmed that human adenovirus (HAdV) infection was related to these outbreaks. Further studies involving sequence determination and phylogenetic analysis based on the penton base, hexon, and fiber genes indicated that human adenovirus type 8 (HAdV-8), belonging to species D, was responsible for the outbreaks. This is the first report of a HAdV-8 associated EKC outbreak in mainland of China, and the results of this study are expected to provide support for future research into HAdV-8 in China.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Adenovirus Humanos / Adenovírus Humanos / Conjuntivite Viral / Surtos de Doenças Limite: Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Adenovirus Humanos / Adenovírus Humanos / Conjuntivite Viral / Surtos de Doenças Limite: Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article