Dramatic response to alectinib in inflammatory myofibroblastic tumor with anaplastic lymphoma kinase fusion gene.
Jpn J Clin Oncol
; 47(12): 1189-1192, 2017 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-28977547
ABSTRACT
Inflammatory myofibroblastic tumor (IMT) is a neoplasm characterized by the proliferaton of myofibroblasts with the infiltration of inflammatory cells. There is no standard treatment for patients with recurrent or metastatic IMT. We describe here a patient with hyper-progressive IMT with an anaplastic lymphoma kinase (ALK) fusion gene that dramatically responded to alectinib without adverse events. His dramatic and enduring response supports the observation that alectinib may be considered a good treatment option for rare aggressive ALK-positive tumors.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piperidinas
/
Carbazóis
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Proteínas de Fusão Oncogênica
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Receptores Proteína Tirosina Quinases
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Granuloma de Células Plasmáticas
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Inflamação
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Jpn J Clin Oncol
Ano de publicação:
2017
Tipo de documento:
Article