APOBEC Enzymes as Targets for Virus and Cancer Therapy.

Olson, Margaret E; Harris, Reuben S; Harki, Daniel A

Olson, Margaret E; Harris, Reuben S; Harki, Daniel A.

Afiliação

Olson ME; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
Harris RS; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Stem Cell Institute, University of Minnesota, Minneapolis, MN 55455, USA.
Harki DA; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA; Stem Cell Institute, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: daharki@umn.edu.

Cell Chem Biol ; 25(1): 36-49, 2018 01 18.

Article em En | MEDLINE | ID: mdl-29153851

Assuntos

Desaminases APOBEC/antagonistas & inibidores; Fármacos Anti-HIV/farmacologia; Antineoplásicos/farmacologia; Inibidores Enzimáticos/farmacologia; HIV-1/efeitos dos fármacos; Neoplasias/tratamento farmacológico; Desaminases APOBEC/metabolismo; Fármacos Anti-HIV/química; Antineoplásicos/química; Inibidores Enzimáticos/química; HIV-1/enzimologia; Humanos; Neoplasias/enzimologia

Palavras-chave

APOBEC; cancer; chemical probes; cytosine-to-uracil; mutation; virus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Fármacos Anti-HIV / Inibidores Enzimáticos / Desaminases APOBEC / Neoplasias / Antineoplásicos Limite: Humans Idioma: En Revista: Cell Chem Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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