Impaired beta cell sensitivity to incretins in type 2 diabetes is insufficiently compensated by higher incretin response.

Tura, A; Bagger, J I; Ferrannini, E; Holst, J J; Knop, F K; Vilsbøll, T; Mari, A

Tura, A; Bagger, J I; Ferrannini, E; Holst, J J; Knop, F K; Vilsbøll, T; Mari, A.

Afiliação

Tura A; CNR Institute of Neuroscience, Padova, Italy.
Bagger JI; Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Ferrannini E; Department of Internal Medicine, University of Pisa School of Medicine, Pisa, Italy; CNR Institute of Clinical Physiology, Pisa, Italy.
Holst JJ; The NNF Center for Basic Metabolic Research, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Knop FK; Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark; The NNF Center for Basic Metabolic Research, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Facult
Vilsbøll T; Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Mari A; CNR Institute of Neuroscience, Padova, Italy. Electronic address: andrea.mari@cnr.it.

Nutr Metab Cardiovasc Dis ; 27(12): 1123-1129, 2017 Dec.

Article em En | MEDLINE | ID: mdl-29162361

Assuntos

Glicemia/efeitos dos fármacos; Diabetes Mellitus Tipo 2/sangue; Polipeptídeo Inibidor Gástrico/sangue; Peptídeo 1 Semelhante ao Glucagon/sangue; Incretinas/sangue; Células Secretoras de Insulina/metabolismo; Insulina/sangue; Idoso; Biomarcadores/sangue; Glicemia/metabolismo; Estudos de Casos e Controles; Dinamarca; Diabetes Mellitus Tipo 2/diagnóstico; Feminino; Teste de Tolerância a Glucose; Humanos; Insulina/metabolismo; Secreção de Insulina; Masculino; Pessoa de Meia-Idade; Modelos Biológicos; Fatores de Tempo

Palavras-chave

Glucagon-like Peptide-1; Glucose-dependent insulinotropic peptide; Incretin effect; Incretin sensitivity; Insulin secretion; Mathematical model; Oral glucose tolerance test; Type 2 diabetes mellitus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicemia / Polipeptídeo Inibidor Gástrico / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Peptídeo 1 Semelhante ao Glucagon / Incretinas / Insulina Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Nutr Metab Cardiovasc Dis Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / CIENCIAS DA NUTRICAO / METABOLISMO Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália

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