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Antifungal Activity and Action Mode of Cuminic Acid from the Seeds of Cuminum cyminum L. against Fusarium oxysporum f. sp. Niveum (FON) Causing Fusarium Wilt on Watermelon.
Sun, Yang; Wang, Yong; Han, Li Rong; Zhang, Xing; Feng, Jun Tao.
Afiliação
  • Sun Y; Research and Development Center of Biorational Pesticide, Northwest A & F University, Yangling 712100, China. sunyang136592@nwsuaf.edu.cn.
  • Wang Y; Research and Development Center of Biorational Pesticide, Northwest A & F University, Yangling 712100, China. wy2010102163@163.com.
  • Han LR; Research and Development Center of Biorational Pesticide, Northwest A & F University, Yangling 712100, China. hlr4119@126.com.
  • Zhang X; Research and Development Center of Biorational Pesticide, Northwest A & F University, Yangling 712100, China. zhxing1952@gmail.com.
  • Feng JT; Engineering and Research Center of Biological Pesticide of Shaanxi Province, Yangling 712100, China. zhxing1952@gmail.com.
Molecules ; 22(12)2017 Nov 30.
Article em En | MEDLINE | ID: mdl-29189726
ABSTRACT
In order to develop a novel biofungicide, the antifungal activity and action mode of cuminic acid from the seed of Cuminum cyminum L. against Fusarium oxysporum f. sp. niveum (FON) on watermelon was determined systematically. In this study, the median effective concentration (EC50) value for cuminic acid in inhibiting mycelial growth of FON was 22.53 µg/mL. After treatment with cuminic acid, the mycelial morphology was seriously influenced; cell membrane permeability and glycerol content were increased markedly, but pigment and mycotoxin (mainly fusaric acid) were significantly decreased. Synthesis genes of bikaverin (Bike1, Bike2 and Bike3) and fusaric acid (FUB1, FUB2, FUB3 and FUB4) both were downregulated compared with the control, as confirmed by quantitative RT-PCR. In greenhouse experiments, cuminic acid at all concentrations displayed significant bioactivities against FON. Importantly, significant enhancement of activities of SOD, POD, CAT and decrease of MDA content were observed after in vivo cuminic acid treatment on watermelon leaves. These indicated that cuminic acid not only showed high antifungal activity, but also could enhance the self-defense system of the host plant. Above all, cuminic acid showed the potential as a biofungicide to control FON.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sementes / Extratos Vegetais / Cuminum / Fusarium / Antifúngicos Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sementes / Extratos Vegetais / Cuminum / Fusarium / Antifúngicos Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China